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Na(V)1.8 channels are expressed in large, as well as small, diameter sensory afferent neurons

Sensory neurons in the dorsal root ganglia (DRG) express a subset of voltage dependent sodium channels (Na(V)) including Na(V)1.1, 1.6, 1.7, 1.8 and 1.9. Previous work supported preferential localization of Na(V)1.8 channels to small-medium diameter, nociceptive afferent neurons. However, we recentl...

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Detalles Bibliográficos
Autores principales: Ramachandra, Renuka, McGrew, Stephanie Y., Baxter, James C., Howard, Jason R., Elmslie, Keith S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589279/
https://www.ncbi.nlm.nih.gov/pubmed/23064159
http://dx.doi.org/10.4161/chan.22445