Cargando…

Strong activation of bile acid-sensitive ion channel (BASIC) by ursodeoxycholic acid

Bile acid-sensitive ion channel (BASIC) is a member of the DEG/ENaC gene family of unknown function. Rat BASIC (rBASIC) is inactive at rest. We have recently shown that cholangiocytes, the epithelial cells lining the bile ducts, are the main site of BASIC expression in the liver and identified bile...

Descripción completa

Detalles Bibliográficos
Autores principales: Wiemuth, Dominik, Sahin, Hacer, Lefèvre, Cathérine M.T., Wasmuth, Hermann E., Gründer, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589280/
https://www.ncbi.nlm.nih.gov/pubmed/23064163
http://dx.doi.org/10.4161/chan.22406