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Strong activation of bile acid-sensitive ion channel (BASIC) by ursodeoxycholic acid
Bile acid-sensitive ion channel (BASIC) is a member of the DEG/ENaC gene family of unknown function. Rat BASIC (rBASIC) is inactive at rest. We have recently shown that cholangiocytes, the epithelial cells lining the bile ducts, are the main site of BASIC expression in the liver and identified bile...
Autores principales: | Wiemuth, Dominik, Sahin, Hacer, Lefèvre, Cathérine M.T., Wasmuth, Hermann E., Gründer, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589280/ https://www.ncbi.nlm.nih.gov/pubmed/23064163 http://dx.doi.org/10.4161/chan.22406 |
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