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Clonal Expansions of CD8(+) T Cells with IL-10 Secreting Capacity Occur during Chronic Mycobacterium tuberculosis Infection

The exact role of CD8(+) T cells during Mycobacterium tuberculosis (Mtb) infection has been heavily debated, yet it is generally accepted that CD8(+) T cells contribute to protection against Mtb. In this study, however, we show that the Mtb-susceptible CBA/J mouse strain accumulates large numbers of...

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Detalles Bibliográficos
Autores principales: Cyktor, Joshua C., Carruthers, Bridget, Beamer, Gillian L., Turner, Joanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589362/
https://www.ncbi.nlm.nih.gov/pubmed/23472214
http://dx.doi.org/10.1371/journal.pone.0058612