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Aberrant Gene Expression and Sexually Incompatible Genomic Imprinting in Oocytes Derived from XY Mouse Embryonic Stem Cells In Vitro

Mouse embryonic stem cells (ESCs) have the potential to differentiate into germ cells (GCs) in vivo and in vitro. Interestingly, XY ESCs can give rise to both male and female GCs in culture, irrespective of the genetic sex. Recent studies showed that ESC-derived primordial GCs contributed to functio...

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Detalles Bibliográficos
Autores principales: Nitta, Mai, Imamura, Masanori, Inoue, Yu, Kunitomo, Yasuo, Lin, Zachary Yu-Ching, Ogawa, Takuya, Yogo, Keiichiro, Ishida-Kitagawa, Norihiro, Fukunaga, Noritaka, Okano, Hideyuki, Sato, Eimei, Takeya, Tatsuo, Miyoshi, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589367/
https://www.ncbi.nlm.nih.gov/pubmed/23472205
http://dx.doi.org/10.1371/journal.pone.0058555