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Aberrant Gene Expression and Sexually Incompatible Genomic Imprinting in Oocytes Derived from XY Mouse Embryonic Stem Cells In Vitro
Mouse embryonic stem cells (ESCs) have the potential to differentiate into germ cells (GCs) in vivo and in vitro. Interestingly, XY ESCs can give rise to both male and female GCs in culture, irrespective of the genetic sex. Recent studies showed that ESC-derived primordial GCs contributed to functio...
Autores principales: | Nitta, Mai, Imamura, Masanori, Inoue, Yu, Kunitomo, Yasuo, Lin, Zachary Yu-Ching, Ogawa, Takuya, Yogo, Keiichiro, Ishida-Kitagawa, Norihiro, Fukunaga, Noritaka, Okano, Hideyuki, Sato, Eimei, Takeya, Tatsuo, Miyoshi, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589367/ https://www.ncbi.nlm.nih.gov/pubmed/23472205 http://dx.doi.org/10.1371/journal.pone.0058555 |
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