The Impact of 3′UTR Variants on Differential Expression of Candidate Cancer Susceptibility Genes

Variants in regulatory regions are predicted to play an important role in disease susceptibility of common diseases. Polymorphisms mapping to microRNA (miRNA) binding sites have been shown to disrupt the ability of miRNAs to target genes resulting in differential mRNA and protein expression. Skin tu...

Descripción completa

Detalles Bibliográficos
Autores principales: Skeeles, Laura E., Fleming, Jessica L., Mahler, Kimberly L., Toland, Amanda Ewart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589377/
https://www.ncbi.nlm.nih.gov/pubmed/23472213
http://dx.doi.org/10.1371/journal.pone.0058609

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589377/
https://www.ncbi.nlm.nih.gov/pubmed/23472213
http://dx.doi.org/10.1371/journal.pone.0058609

Ejemplares similares