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Concordant and Discordant Regulation of Target Genes by miR-31 and Its Isoforms

It has been shown that imprecise cleavage of a primary or precursor RNA by Drosha or Dicer, respectively, may yield a group of microRNA (miRNA) variants designated as “isomiR”. Variations in the relative abundance of isoforms for a given miRNA among different species and different cell types beg the...

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Detalles Bibliográficos
Autores principales: Chan, Yu-Tzu, Lin, You-Chin, Lin, Ruey-Jen, Kuo, Huan-Hsien, Thang, Wai-Cheng, Chiu, Kuo-Ping, Yu, Alice L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589381/
https://www.ncbi.nlm.nih.gov/pubmed/23472152
http://dx.doi.org/10.1371/journal.pone.0058169