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ATP Induces NO Production in Hippocampal Neurons by P2X(7) Receptor Activation Independent of Glutamate Signaling

To assess the putative role of adenosine triphosphate (ATP) upon nitric oxide (NO) production in the hippocampus, we used as a model both rat hippocampal slices and isolated hippocampal neurons in culture, lacking glial cells. In hippocampal slices, additions of exogenous ATP or 2′(3′)-O-(4-Benzoylb...

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Detalles Bibliográficos
Autores principales: Codocedo, Juan Francisco, Godoy, Juan Alejandro, Poblete, Maria Ines, Inestrosa, Nibaldo C., Huidobro-Toro, Juan Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589399/
https://www.ncbi.nlm.nih.gov/pubmed/23472093
http://dx.doi.org/10.1371/journal.pone.0057626