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Identity-by-Descent Mapping to Detect Rare Variants Conferring Susceptibility to Multiple Sclerosis

Genome-wide association studies (GWAS) have identified around 60 common variants associated with multiple sclerosis (MS), but these loci only explain a fraction of the heritability of MS. Some missing heritability may be caused by rare variants that have been suggested to play an important role in t...

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Detalles Bibliográficos
Autores principales: Lin, Rui, Charlesworth, Jac, Stankovich, Jim, Perreau, Victoria M., Brown, Matthew A., Taylor, Bruce V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589405/
https://www.ncbi.nlm.nih.gov/pubmed/23472070
http://dx.doi.org/10.1371/journal.pone.0056379