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Probing the Interaction Forces of Prostate Cancer Cells with Collagen I and Bone Marrow Derived Stem Cells on the Single Cell Level

Adhesion of metastasizing prostate carcinoma cells was quantified for two carcinoma model cell lines LNCaP (lymph node-specific) and PC3 (bone marrow-specific). By time-lapse microscopy and force spectroscopy we found PC3 cells to preferentially adhere to bone marrow-derived mesenchymal stem cells (...

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Detalles Bibliográficos
Autores principales: Sariisik, Ediz, Docheva, Denitsa, Padula, Daniela, Popov, Cvetan, Opfer, Jan, Schieker, Matthias, Clausen-Schaumann, Hauke, Benoit, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589411/
https://www.ncbi.nlm.nih.gov/pubmed/23472100
http://dx.doi.org/10.1371/journal.pone.0057706