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14-3-3ε Mediates the Cell Fate Decision-Making Pathways in Response of Hepatocellular Carcinoma to Bleomycin-Induced DNA Damage

BACKGROUND: Lack of understanding of the response of hepatocellular carcinoma (HCC) to anticancer drugs causes the high mortality of HCC patients. Bleomycin (BLM) that induces DNA damage is clinically used for cancer therapy, while the mechanism underlying BLM-induced DNA damage response (DDR) in HC...

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Detalles Bibliográficos
Autores principales: Tang, Siwei, Bao, Huimin, Zhang, Yang, Yao, Jun, Yang, Pengyuan, Chen, Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589417/
https://www.ncbi.nlm.nih.gov/pubmed/23472066
http://dx.doi.org/10.1371/journal.pone.0055268