Expression of Recipient CD47 on Rat Insulinoma Cell Xenografts Prevents Macrophage-Mediated Rejection through SIRPα Inhibitory Signaling in Mice

We have previously proven that the interspecies incompatibility of CD47 is responsible for in vitro phagocytosis of xenogeneic cells by host macrophages. Utilizing an in vivo model in the present study, we investigated whether genetically engineered expression of mouse CD47 in rat insulinoma cells (...

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Detalles Bibliográficos
Autores principales: Teraoka, Yoshifumi, Ide, Kentaro, Morimoto, Hiroshi, Tahara, Hiroyuki, Ohdan, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589424/
https://www.ncbi.nlm.nih.gov/pubmed/23472187
http://dx.doi.org/10.1371/journal.pone.0058359

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589424/
https://www.ncbi.nlm.nih.gov/pubmed/23472187
http://dx.doi.org/10.1371/journal.pone.0058359

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