Structural Characterization of the Self-Association of the Death Domain of p75(NTR)

The neurotrophin receptor p75(NTR) conveys multiple signals via its intracellular death domain. However, how the death domain is activated and interacts with downstream adaptors remains unclear. Here, we report two crystal structures of the p75(NTR) death domain in the form of a non-covalent asymmet...

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Detalles Bibliográficos
Autores principales: Qu, Qianhui, Chen, Jun, Wang, Yizhi, Gui, Wenjun, Wang, Li, Fan, Zusen, Jiang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589453/
https://www.ncbi.nlm.nih.gov/pubmed/23472109
http://dx.doi.org/10.1371/journal.pone.0057839

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589453/
https://www.ncbi.nlm.nih.gov/pubmed/23472109
http://dx.doi.org/10.1371/journal.pone.0057839

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