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Large-Scale Functional Purification of Recombinant HIV-1 Capsid

During human immunodeficiency virus type-1 (HIV-1) virion maturation, capsid proteins undergo a major rearrangement to form a conical core that protects the viral nucleoprotein complexes. Mutations in the capsid sequence that alter the stability of the capsid core are deleterious to viral infectivit...

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Detalles Bibliográficos
Autores principales: Hung, Magdeleine, Niedziela-Majka, Anita, Jin, Debi, Wong, Melanie, Leavitt, Stephanie, Brendza, Katherine M., Liu, Xiaohong, Sakowicz, Roman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589475/
https://www.ncbi.nlm.nih.gov/pubmed/23472130
http://dx.doi.org/10.1371/journal.pone.0058035