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Cytotoxic Activity and Apoptosis-Inducing Potential of Di-spiropyrrolidino and Di-spiropyrrolizidino Oxindole Andrographolide Derivatives

Anticancer role of andrographolide is well documented. To find novel potent derivatives with improved cytotoxicity than andrographolide on cancer cells, two series of di-spiropyrrolidino- and di-spiropyrrolizidino oxindole andrographolide derivatives prepared by cyclo-addition of azomethine ylide al...

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Detalles Bibliográficos
Autores principales: Dey, Sumit Kumar, Bose, Dipayan, Hazra, Abhijit, Naskar, Subhendu, Nandy, Abhishek, Munda, Rudra Narayan, Das, Subhadip, Chatterjee, Nabanita, Mondal, Nirup Bikash, Banerjee, Sukdeb, Saha, Krishna Das
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589478/
https://www.ncbi.nlm.nih.gov/pubmed/23472133
http://dx.doi.org/10.1371/journal.pone.0058055