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Tim-3 Expression Defines Regulatory T Cells in Human Tumors

Tim-3, a member of the novel Tim (T cell immunoglobulin and mucin domain) family, has been reported to negatively regulate the immune responses against viral infection and had implications for autoimmune disease. However, the nature and role of Tim-3(+) CD4 T cells in human tumors remain largely unk...

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Detalles Bibliográficos
Autores principales: Yan, Jing, Zhang, Yi, Zhang, Jing-Ping, Liang, Jing, Li, Lian, Zheng, Limin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589491/
https://www.ncbi.nlm.nih.gov/pubmed/23526963
http://dx.doi.org/10.1371/journal.pone.0058006