Spatial congregation of STAT binding directs selective nuclear architecture during T-cell functional differentiation

Higher-order genome organization shows tissue-specific patterns. However, functional relevance and the mechanisms shaping the genome architecture are poorly understood. Here we report a profound shift from promiscuous to highly selective genome organization that accompanies the effector lineage choi...

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Detalles Bibliográficos
Autores principales: Hakim, Ofir, Sung, Myong-Hee, Nakayamada, Shingo, Voss, Ty C., Baek, Songjoon, Hager, Gordon L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589535/
https://www.ncbi.nlm.nih.gov/pubmed/23212947
http://dx.doi.org/10.1101/gr.147652.112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589535/
https://www.ncbi.nlm.nih.gov/pubmed/23212947
http://dx.doi.org/10.1101/gr.147652.112

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