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High-throughput sequencing reveals extraordinary fluidity of miRNA, piRNA, and siRNA pathways in nematodes

The nematode Caenorhabditis elegans contains each of the broad classes of eukaryotic small RNAs, including microRNAs (miRNAs), endogenous small-interfering RNAs (endo-siRNAs), and piwi-interacting RNAs (piRNAs). To better understand the evolution of these regulatory RNAs, we deep-sequenced small RNA...

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Detalles Bibliográficos
Autores principales: Shi, Zhen, Montgomery, Taiowa A., Qi, Yan, Ruvkun, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589538/
https://www.ncbi.nlm.nih.gov/pubmed/23363624
http://dx.doi.org/10.1101/gr.149112.112