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Genotype imputation via matrix completion

Most current genotype imputation methods are model-based and computationally intensive, taking days to impute one chromosome pair on 1000 people. We describe an efficient genotype imputation method based on matrix completion. Our matrix completion method is implemented in MATLAB and tested on real d...

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Detalles Bibliográficos
Autores principales: Chi, Eric C., Zhou, Hua, Chen, Gary K., Del Vecchyo, Diego Ortega, Lange, Kenneth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589539/
https://www.ncbi.nlm.nih.gov/pubmed/23233546
http://dx.doi.org/10.1101/gr.145821.112