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Tolerogenic and Activatory Plasmacytoid Dendritic Cells in Autoimmunity

Plasmacytoid dendritic cells (pDCs) are a particular subset of DCs that link innate and adaptive immunity. They are responsible for the substantial production of type 1 interferon (IFN-I) in response to viral RNA or DNA through activation of TLR7 and 9. Furthermore, pDCs present antigens (Ag) and in...

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Detalles Bibliográficos
Autores principales: Guéry, Leslie, Hugues, Stéphanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589693/
https://www.ncbi.nlm.nih.gov/pubmed/23508732
http://dx.doi.org/10.3389/fimmu.2013.00059