Tumor Evolution in Space: The Effects of Competition Colonization Tradeoffs on Tumor Invasion Dynamics

We apply competition colonization tradeoff models to tumor growth and invasion dynamics to explore the hypothesis that varying selection forces will result in predictable phenotypic differences in cells at the tumor invasive front compared to those in the core. Spatially, ecologically, and evolution...

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Detalles Bibliográficos
Autores principales: Orlando, Paul A., Gatenby, Robert A., Brown, Joel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589695/
https://www.ncbi.nlm.nih.gov/pubmed/23508890
http://dx.doi.org/10.3389/fonc.2013.00045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589695/
https://www.ncbi.nlm.nih.gov/pubmed/23508890
http://dx.doi.org/10.3389/fonc.2013.00045

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