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PASE: a novel method for functional prediction of amino acid substitutions based on physicochemical properties
Background: Non-synonymous single-nucleotide polymorphisms (nsSNPs) within the coding regions of genes causing amino acid substitutions (AASs) may have a large impact on protein function. The possibilities to identify nsSNPs across genomes have increased notably with the advent of next-generation se...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589708/ https://www.ncbi.nlm.nih.gov/pubmed/23508070 http://dx.doi.org/10.3389/fgene.2013.00021 |