Lentiviral vector-based insertional mutagenesis identifies genes associated with liver cancer

Transposons and γ-retroviruses have been efficiently used as insertional mutagens in different tissues to identify molecular culprits of cancer. However, these systems are characterized by recurring integrations that accumulate in tumor cells, hampering the identification of early cancer-driving eve...

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Detalles Bibliográficos
Autores principales: Ranzani, Marco, Cesana, Daniela, Bartholomae, Cynthia C., Sanvito, Francesca, Pala, Mauro, Benedicenti, Fabrizio, Gallina, Pierangela, Sergi, Lucia Sergi, Merella, Stefania, Bulfone, Alessandro, Doglioni, Claudio, von Kalle, Christof, Kim, Yoon Jun, Schmidt, Manfred, Tonon, Giovanni, Naldini, Luigi, Montini, Eugenio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589714/
https://www.ncbi.nlm.nih.gov/pubmed/23314173
http://dx.doi.org/10.1038/nmeth.2331

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589714/
https://www.ncbi.nlm.nih.gov/pubmed/23314173
http://dx.doi.org/10.1038/nmeth.2331

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