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Genetic background influences adaptation to cardiac hypertrophy and Ca(2+) handling gene expression

Genetic variability has a profound effect on the development of cardiac hypertrophy in response to stress. Consequently, using a variety of inbred mouse strains with known genetic profiles may be powerful models for studying the response to cardiovascular stress. To explore this approach we looked a...

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Detalles Bibliográficos
Autores principales: Waters, Steve B., Diak, Douglass M., Zuckermann, Matthew, Goldspink, Paul H., Leoni, Lara, Roman, Brian B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589715/
https://www.ncbi.nlm.nih.gov/pubmed/23508205
http://dx.doi.org/10.3389/fphys.2013.00011