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Toll like receptor 4 mediates cell death in a mouse MPTP model of Parkinson disease

In mammalians, toll-like receptors (TLR) signal-transduction pathways induce the expression of a variety of immune-response genes, including inflammatory cytokines. It is therefore plausible to assume that TLRs are mediators in glial cells triggering the release of cytokines that ultimately kill DA...

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Detalles Bibliográficos
Autores principales: Noelker, Carmen, Morel, Lydie, Lescot, Thomas, Osterloh, Anke, Alvarez-Fischer, Daniel, Breloer, Minka, Henze, Carmen, Depboylu, Candan, Skrzydelski, Delphine, Michel, Patrick P., Dodel, Richard C., Lu, Lixia, Hirsch, Etienne C., Hunot, Stéphane, Hartmann, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589722/
https://www.ncbi.nlm.nih.gov/pubmed/23462811
http://dx.doi.org/10.1038/srep01393