Wortmannin efficiently suppresses the recovery from radiation-induced damage in pimonidazole-unlabeled quiescent tumor cell population

Labeling of proliferating (P) cells in mice bearing EL4 tumors was achieved by continuous administration of 5-bromo-2′-deoxyuridine (BrdU). Tumors were irradiated with γ-rays at 1 h after pimonidazole administration followed by caffeine or wortmannin treatment. Twenty-four hours later, assessment of...

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Detalles Bibliográficos
Autores principales: Masunaga, Shin-ichiro, Sakurai, Yoshinori, Tanaka, Hiroki, Suzuki, Minoru, Kondo, Natsuko, Narabayashi, Masaru, Maruhashi, Akira, Ono, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589932/
https://www.ncbi.nlm.nih.gov/pubmed/23097299
http://dx.doi.org/10.1093/jrr/rrs094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589932/
https://www.ncbi.nlm.nih.gov/pubmed/23097299
http://dx.doi.org/10.1093/jrr/rrs094

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