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Effects of expression level of DNA repair-related genes involved in the NHEJ pathway on radiation-induced cognitive impairment
Cranial radiation therapy can induce cognitive decline. Impairments of hippocampal neurogenesis are thought to be a paramountly important mechanism underlying radiation-induced cognitive dysfunction. In the mature nervous system, DNA double-strand breaks (DSBs) are mainly repaired by non-homologous...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589933/ https://www.ncbi.nlm.nih.gov/pubmed/23135157 http://dx.doi.org/10.1093/jrr/rrs095 |