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Effects of expression level of DNA repair-related genes involved in the NHEJ pathway on radiation-induced cognitive impairment

Cranial radiation therapy can induce cognitive decline. Impairments of hippocampal neurogenesis are thought to be a paramountly important mechanism underlying radiation-induced cognitive dysfunction. In the mature nervous system, DNA double-strand breaks (DSBs) are mainly repaired by non-homologous...

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Detalles Bibliográficos
Autores principales: Zhang, Li-Yuan, Chen, Lie-Song, Sun, Rui, JI, Sheng-Jun, Ding, Yan-Yan, Wu, Jia, Tian, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589933/
https://www.ncbi.nlm.nih.gov/pubmed/23135157
http://dx.doi.org/10.1093/jrr/rrs095