Aggregation of Human S100A8 and S100A9 Amyloidogenic Proteins Perturbs Proteostasis in a Yeast Model

Amyloid aggregates of the calcium-binding EF-hand proteins, S100A8 and S100A9, have been found in the corpora amylacea of patients with prostate cancer and may play a role in carcinogenesis. Here we present a novel model system using the yeast Saccharomyces cerevisiae to study human S100A8 and S100A...

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Detalles Bibliográficos
Autores principales: Eremenko, Ekaterina, Ben-Zvi, Anat, Morozova-Roche, Ludmilla A., Raveh, Dina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590125/
https://www.ncbi.nlm.nih.gov/pubmed/23483999
http://dx.doi.org/10.1371/journal.pone.0058218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590125/
https://www.ncbi.nlm.nih.gov/pubmed/23483999
http://dx.doi.org/10.1371/journal.pone.0058218

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