Evaluating the Effect of Ionic Strength on Duplex Stability for PNA Having Negatively or Positively Charged Side Chains

The enhanced thermodynamic stability of PNA:DNA and PNA:RNA duplexes compared with DNA:DNA and DNA:RNA duplexes has been attributed in part to the lack of electrostatic repulsion between the uncharged PNA backbone and negatively charged DNA or RNA backbone. However, there are no previously reported...

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Detalles Bibliográficos
Autores principales: De Costa, N. Tilani S., Heemstra, Jennifer M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590165/
https://www.ncbi.nlm.nih.gov/pubmed/23484047
http://dx.doi.org/10.1371/journal.pone.0058670

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590165/
https://www.ncbi.nlm.nih.gov/pubmed/23484047
http://dx.doi.org/10.1371/journal.pone.0058670

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