Increased Sensitivity to Chemotherapy Induced by CpG-ODN Treatment Is Mediated by microRNA Modulation

We recently reported that peritumoral CpG-ODN treatment, activating TLR-9 expressing cells in tumor microenvironment, induces modulation of genes involved in DNA repair and sensitizes cancer cells to DNA-damaging cisplatin treatment. Here, we investigated whether this treatment induces modulation of...

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Detalles Bibliográficos
Autores principales: De Cecco, Loris, Berardi, Martina, Sommariva, Michele, Cataldo, Alessandra, Canevari, Silvana, Mezzanzanica, Delia, Iorio, Marilena V., Tagliabue, Elda, Balsari, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590172/
https://www.ncbi.nlm.nih.gov/pubmed/23484053
http://dx.doi.org/10.1371/journal.pone.0058849

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590172/
https://www.ncbi.nlm.nih.gov/pubmed/23484053
http://dx.doi.org/10.1371/journal.pone.0058849

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