The CXCR4 Antagonist AMD3465 Regulates Oncogenic Signaling and Invasiveness In Vitro and Prevents Breast Cancer Growth and Metastasis In Vivo

CXCR4, the receptor for stromal-derived factor-1, is reportedly involved in breast carcinogenesis. However, the mechanisms through which CXCR4 contributes to breast cancer cell growth and metastases are poorly understood. In this study, we examined the putative in vitro and in vivo anti-cancer effec...

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Detalles Bibliográficos
Autores principales: Ling, Xiaoyang, Spaeth, Erika, Chen, Ye, Shi, Yuexi, Zhang, Weiguo, Schober, Wendy, Hail, Numsen, Konopleva, Marina, Andreeff, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590173/
https://www.ncbi.nlm.nih.gov/pubmed/23484027
http://dx.doi.org/10.1371/journal.pone.0058426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590173/
https://www.ncbi.nlm.nih.gov/pubmed/23484027
http://dx.doi.org/10.1371/journal.pone.0058426

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