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Inhibiting the Growth of Pancreatic Adenocarcinoma In Vitro and In Vivo through Targeted Treatment with Designer Gold Nanotherapeutics

BACKGROUND: Pancreatic cancer is one of the deadliest of all human malignancies with limited options for therapy. Here, we report the development of an optimized targeted drug delivery system to inhibit advanced stage pancreatic tumor growth in an orthotopic mouse model. METHOD/PRINCIPAL FINDINGS: T...

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Detalles Bibliográficos
Autores principales: Kudgus, Rachel A., Szabolcs, Annamaria, Khan, Jameel Ahmad, Walden, Chad A., Reid, Joel M., Robertson, J. David, Bhattacharya, Resham, Mukherjee, Priyabrata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590245/
https://www.ncbi.nlm.nih.gov/pubmed/23483913
http://dx.doi.org/10.1371/journal.pone.0057522