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Inhibiting the Growth of Pancreatic Adenocarcinoma In Vitro and In Vivo through Targeted Treatment with Designer Gold Nanotherapeutics
BACKGROUND: Pancreatic cancer is one of the deadliest of all human malignancies with limited options for therapy. Here, we report the development of an optimized targeted drug delivery system to inhibit advanced stage pancreatic tumor growth in an orthotopic mouse model. METHOD/PRINCIPAL FINDINGS: T...
Autores principales: | Kudgus, Rachel A., Szabolcs, Annamaria, Khan, Jameel Ahmad, Walden, Chad A., Reid, Joel M., Robertson, J. David, Bhattacharya, Resham, Mukherjee, Priyabrata |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590245/ https://www.ncbi.nlm.nih.gov/pubmed/23483913 http://dx.doi.org/10.1371/journal.pone.0057522 |
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