Inhibiting autophagy potentiates the anticancer activity of IFN1@/IFNα in chronic myeloid leukemia cells

IFN1@ (interferon, type 1, cluster, also called IFNα) has been extensively studied as a treatment for patients with chronic myeloid leukemia (CML). The mechanism of anticancer activity of IFN1@ is complex and not well understood. Here, we demonstrate that autophagy, a mechanism of cellular homeostas...

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Detalles Bibliográficos
Autores principales: Zhu, Shan, Cao, Lizhi, Yu, Yan, Yang, Liangchun, Yang, Minghua, Liu, Ke, Huang, Jun, Kang, Rui, Livesey, Kristen M., Tang, Daolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Basic Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590253/
https://www.ncbi.nlm.nih.gov/pubmed/23242206
http://dx.doi.org/10.4161/auto.22923

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590253/
https://www.ncbi.nlm.nih.gov/pubmed/23242206
http://dx.doi.org/10.4161/auto.22923

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