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Bioluminescence Imaging Reveals Dynamics of Beta Cell Loss in the Non-Obese Diabetic (NOD) Mouse Model

We generated a mouse model (MIP-Luc-VU-NOD) that enables non-invasive bioluminescence imaging (BLI) of beta cell loss during the progression of autoimmune diabetes and determined the relationship between BLI and disease progression. MIP-Luc-VU-NOD mice displayed insulitis and a decline in biolumines...

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Detalles Bibliográficos
Autores principales: Virostko, John, Radhika, Armandla, Poffenberger, Greg, Dula, Adrienne N., Moore, Daniel J., Powers, Alvin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590285/
https://www.ncbi.nlm.nih.gov/pubmed/23483929
http://dx.doi.org/10.1371/journal.pone.0057784