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Bioluminescence Imaging Reveals Dynamics of Beta Cell Loss in the Non-Obese Diabetic (NOD) Mouse Model
We generated a mouse model (MIP-Luc-VU-NOD) that enables non-invasive bioluminescence imaging (BLI) of beta cell loss during the progression of autoimmune diabetes and determined the relationship between BLI and disease progression. MIP-Luc-VU-NOD mice displayed insulitis and a decline in biolumines...
Autores principales: | Virostko, John, Radhika, Armandla, Poffenberger, Greg, Dula, Adrienne N., Moore, Daniel J., Powers, Alvin C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590285/ https://www.ncbi.nlm.nih.gov/pubmed/23483929 http://dx.doi.org/10.1371/journal.pone.0057784 |
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