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Ferricytochrome c Directly Oxidizes Aminoacetone to Methylglyoxal, a Catabolite Accumulated in Carbonyl Stress

Age-related diseases are associated with increased production of reactive oxygen and carbonyl species such as methylglyoxal. Aminoacetone, a putative threonine catabolite, is reportedly known to undergo metal-catalyzed oxidation to methylglyoxal, NH(4) (+) ion, and H(2)O(2) coupled with (i) permeabi...

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Detalles Bibliográficos
Autores principales: Sartori, Adriano, Mano, Camila M., Mantovani, Mariana C., Dyszy, Fábio H., Massari, Júlio, Tokikawa, Rita, Nascimento, Otaciro R., Nantes, Iseli L., Bechara, Etelvino J. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590289/
https://www.ncbi.nlm.nih.gov/pubmed/23483930
http://dx.doi.org/10.1371/journal.pone.0057790