CCN2 exerts direct cytoprotective actions in adult cardiac myocytes by activation of the PI3-kinase/Akt/GSK-3β signaling pathway

We recently reported that transgenic mice with cardiac-restricted overexpression of CCN2/CTGF have substantially increased tolerance towards ischemia/reperfusion injury. The purpose of this study was to investigate to what extent fully differentiated cardiac myocytes are direct targets of CCN2, and...

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Detalles Bibliográficos
Autores principales: Moe, Ingvild Tronstad, Pham, Tuyet Anh, Hagelin, Else Marie Valbjørn, Ahmed, Mohammad Shakil, Attramadal, Håvard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590365/
https://www.ncbi.nlm.nih.gov/pubmed/23208610
http://dx.doi.org/10.1007/s12079-012-0183-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590365/
https://www.ncbi.nlm.nih.gov/pubmed/23208610
http://dx.doi.org/10.1007/s12079-012-0183-1

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