Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex

Co-receptors add complexity to cell-cell signaling systems. The secreted semaphorin 3s (Sema3s) require a co-receptor, neuropilin (Nrp), to signal through plexin As (PlxnAs) in functions ranging from axon guidance to bone homeostasis, but the co-receptor’s role is obscure. Here we present the low re...

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Detalles Bibliográficos
Autores principales: Janssen, Bert J.C., Malinauskas, Tomas, Weir, Greg A., Cader, M. Zameel, Siebold, Christian, Jones, E. Yvonne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590443/
https://www.ncbi.nlm.nih.gov/pubmed/23104057
http://dx.doi.org/10.1038/nsmb.2416

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590443/
https://www.ncbi.nlm.nih.gov/pubmed/23104057
http://dx.doi.org/10.1038/nsmb.2416

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