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Circulating microRNAs as biomarkers for early detection of diffuse-type gastric cancer using a mouse model

BACKGROUND: Diffuse-type gastric cancer (DGC) exhibits rapid disease progression and a poor prognosis. There are no effective serum biomarkers for early detection of DGC. We have established an E-cadherin/p53 double conditional knockout (DCKO) mouse line that recapitulates human DGC morphologically...

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Detalles Bibliográficos
Autores principales: Rotkrua, P, Shimada, S, Mogushi, K, Akiyama, Y, Tanaka, H, Yuasa, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590667/
https://www.ncbi.nlm.nih.gov/pubmed/23385731
http://dx.doi.org/10.1038/bjc.2013.30