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Complex epigenetic regulation of Engrailed-2 (EN-2) homeobox gene in the autism cerebellum

The elucidation of epigenetic alterations in the autism brain has potential to provide new insights into the molecular mechanisms underlying abnormal gene expression in this disorder. Given strong evidence that engrailed-2 (EN-2) is a developmentally expressed gene relevant to cerebellar abnormaliti...

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Detalles Bibliográficos
Autores principales: James, S J, Shpyleva, Svitlana, Melnyk, Stepan, Pavliv, Oleksandra, Pogribny, I P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590998/
https://www.ncbi.nlm.nih.gov/pubmed/23423141
http://dx.doi.org/10.1038/tp.2013.8