Conformation-Dependent High-Affinity Potent Ricin-Neutralizing Monoclonal Antibodies

Ricin is a potential biothreat agent with no approved antidote available for ricin poisoning. The aim of this study was to develop potent antibody-based antiricin antidotes. Four strong ricin resistant hybridoma clones secreting antiricin monoclonal antibodies (mAbs) were developed. All four mAbs ar...

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Detalles Bibliográficos
Autores principales: Hu, Wei-Gang, Yin, Junfei, Chau, Damon, Hu, Charles Chen, Lillico, Dustin, Yu, Justin, Negrych, Laurel M., Cherwonogrodzky, John W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591125/
https://www.ncbi.nlm.nih.gov/pubmed/23484120
http://dx.doi.org/10.1155/2013/471346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591125/
https://www.ncbi.nlm.nih.gov/pubmed/23484120
http://dx.doi.org/10.1155/2013/471346

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