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Conformation-Dependent High-Affinity Potent Ricin-Neutralizing Monoclonal Antibodies
Ricin is a potential biothreat agent with no approved antidote available for ricin poisoning. The aim of this study was to develop potent antibody-based antiricin antidotes. Four strong ricin resistant hybridoma clones secreting antiricin monoclonal antibodies (mAbs) were developed. All four mAbs ar...
Autores principales: | Hu, Wei-Gang, Yin, Junfei, Chau, Damon, Hu, Charles Chen, Lillico, Dustin, Yu, Justin, Negrych, Laurel M., Cherwonogrodzky, John W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591125/ https://www.ncbi.nlm.nih.gov/pubmed/23484120 http://dx.doi.org/10.1155/2013/471346 |
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