Glutamine and Alanyl-Glutamine Increase RhoA Expression and Reduce Clostridium difficile Toxin-A-Induced Intestinal Epithelial Cell Damage

Clostridium difficile is a major cause of antibiotic-associated colitis and is associated with significant morbidity and mortality. Glutamine (Gln) is a major fuel for the intestinal cell population. Alanyl-glutamine (Ala-Gln) is a dipeptide that is highly soluble and well tolerated. IEC-6 cells wer...

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Detalles Bibliográficos
Autores principales: Santos, Ana A. Q. A., Braga-Neto, Manuel B., Oliveira, Marcelo R., Freire, Rosemeire S., Barros, Eduardo B., Santiago, Thiago M., Rebelo, Luciana M., Mermelstein, Claudia, Warren, Cirle A., Guerrant, Richard L., Brito, Gerly A. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591182/
https://www.ncbi.nlm.nih.gov/pubmed/23484083
http://dx.doi.org/10.1155/2013/152052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591182/
https://www.ncbi.nlm.nih.gov/pubmed/23484083
http://dx.doi.org/10.1155/2013/152052

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