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Glutamine and Alanyl-Glutamine Increase RhoA Expression and Reduce Clostridium difficile Toxin-A-Induced Intestinal Epithelial Cell Damage
Clostridium difficile is a major cause of antibiotic-associated colitis and is associated with significant morbidity and mortality. Glutamine (Gln) is a major fuel for the intestinal cell population. Alanyl-glutamine (Ala-Gln) is a dipeptide that is highly soluble and well tolerated. IEC-6 cells wer...
Autores principales: | Santos, Ana A. Q. A., Braga-Neto, Manuel B., Oliveira, Marcelo R., Freire, Rosemeire S., Barros, Eduardo B., Santiago, Thiago M., Rebelo, Luciana M., Mermelstein, Claudia, Warren, Cirle A., Guerrant, Richard L., Brito, Gerly A. C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591182/ https://www.ncbi.nlm.nih.gov/pubmed/23484083 http://dx.doi.org/10.1155/2013/152052 |
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