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CpG and Interleukin-15 Synergize to Enhance IFN-γ Production by Activated CD8(+) T Cells
Interleukin-15 (IL-15) regulates the development and maintenance of memory CD8(+) T cells. Paradoxically, we previously reported that IL-15 could enhance CD8(+) T-cell responses to IL-12, a proinflammatory cytokine required for optimal priming of effector CD8(+) T cells. To expand the physiological...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591192/ https://www.ncbi.nlm.nih.gov/pubmed/23509806 http://dx.doi.org/10.1155/2013/924023 |