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CpG and Interleukin-15 Synergize to Enhance IFN-γ Production by Activated CD8(+) T Cells

Interleukin-15 (IL-15) regulates the development and maintenance of memory CD8(+) T cells. Paradoxically, we previously reported that IL-15 could enhance CD8(+) T-cell responses to IL-12, a proinflammatory cytokine required for optimal priming of effector CD8(+) T cells. To expand the physiological...

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Detalles Bibliográficos
Autores principales:	Cobb, Dustin, Guo, Siqi, Smeltz, Ronald B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591192/ https://www.ncbi.nlm.nih.gov/pubmed/23509806 http://dx.doi.org/10.1155/2013/924023

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