Simultaneous Quantification of Mitochondrial DNA Damage and Copy Number in Circulating Blood: A Sensitive Approach to Systemic Oxidative Stress

Systemic oxidative stress is associated with a wide range of pathological conditions. Oxidative DNA damage is frequently measured in circulating lymphocytes. Mitochondrial DNA (mtDNA) is known to be more sensitive to oxidative damage than nuclear DNA but is rarely used for direct measurement of DNA...

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Detalles Bibliográficos
Autores principales: Chan, Sam W., Chevalier, Simone, Aprikian, Armen, Chen, Junjian Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591215/
https://www.ncbi.nlm.nih.gov/pubmed/23484085
http://dx.doi.org/10.1155/2013/157547

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591215/
https://www.ncbi.nlm.nih.gov/pubmed/23484085
http://dx.doi.org/10.1155/2013/157547

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