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Biochemical Characterization and Pharmacological Properties of New Basic PLA(2) BrTX-I Isolated from Bothrops roedingeri (Roedinger's Lancehead) Mertens, 1942, Snake Venom

BrTX-I, a PLA(2), was purified from Bothrops roedingeri venom after only one chromatographic step using reverse-phase HPLC on μ-Bondapak C-18 column. A molecular mass of 14358.69 Da was determined by MALDI-TOF mass spectrometry. Amino acid analysis showed a high content of hydrophobic and basic amin...

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Detalles Bibliográficos
Autores principales: Gomes Heleno, Mauricio Aurelio, Baldasso, Paulo Aparecido, Ponce-Soto, Luis Alberto, Marangoni, Sérgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591238/
https://www.ncbi.nlm.nih.gov/pubmed/23509747
http://dx.doi.org/10.1155/2013/591470